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Toxicological Safety Evaluation of DNA Plasmid Vaccines against HIV-1, Ebola, Severe Acute Respiratory Syndrome, or West Nile Virus Is Similar Despite Differing Plasmid Backbones or Gene-Inserts

The Vaccine Research Center has developed a number of vaccine candidates for different diseases/infectious agents (HIV-1, Severe Acute Respiratory Syndrome virus, West Nile virus, and Ebola virus, plus a plasmid cytokine adjuvant—IL-2/Ig) based on a DNA plasmid vaccine platform. To support the clini...

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Detalhes bibliográficos
Main Authors: Sheets, Rebecca L., Stein, Judith, Manetz, T. Scott, Andrews, Charla, Bailer, Robert, Rathmann, John, Gomez, Phillip L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2366098/
https://ncbi.nlm.nih.gov/pubmed/16569728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfj170
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