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Allele-Specific Up-Regulation of FGFR2 Increases Susceptibility to Breast Cancer

The recent whole-genome scan for breast cancer has revealed the FGFR2 (fibroblast growth factor receptor 2) gene as a locus associated with a small, but highly significant, increase in the risk of developing breast cancer. Using fine-scale genetic mapping of the region, it has been possible to narro...

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Hlavní autoři: Meyer, Kerstin B, Maia, Ana-Teresa, O'Reilly, Martin, Teschendorff, Andrew E, Chin, Suet-Feung, Caldas, Carlos, Ponder, Bruce A. J
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2365982/
https://ncbi.nlm.nih.gov/pubmed/18462018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0060108
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