Interleukin-2 and alpha/beta interferon down-regulate hepatitis B virus gene expression in vivo by tumor necrosis factor-dependent and -independent pathways.

We have recently reported that administration of recombinant tumor necrosis factor alpha (TNF-alpha) to hepatitis B virus (HBV) transgenic mice reduces the hepatic steady-state content of HBV-specific mRNA by up to 80% in the absence of liver cell injury. In the current study, we analyzed the regula...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Guidotti, L G, Guilhot, S, Chisari, F V
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1994
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236579/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8107192/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.3.1265-1270.1994
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