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Role of transforming growth factor-β(1) in down-regulating TNF production by alveolar macrophages during asbestos-induced pulmonary fibrosis

Activation of alveolar macrophages (AM) for tumour necrosis factor production is suppressed initially during the inflammatory response to fibrogenic dusts. We investigated the mechanisms involved in TNF suppression, notably the role of other AM-derived mediators including prostaglandin E(2) (PGE(2))...

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Main Authors: Lemaire, Irma, Ouellet, Sophie
Formato: Artigo
Idioma:Inglês
Publicado: Hindawi Publishing Corporation 1996
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2365768/
https://ncbi.nlm.nih.gov/pubmed/18475695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/S0962935196000063
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