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Bone marrow-derived circulating endothelial precursors do not contribute to vascular endothelium and are not needed for tumor growth

The mechanisms by which bone marrow (BM)-derived stem cells might contribute to angiogenesis and the origin of neovascular endothelial cells (ECs) are controversial. Neovascular ECs have been proposed to originate from VEGF receptor 2-expressing (VEGFR-2+) stem cells mobilized from the BM by VEGF or...

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Detalhes bibliográficos
Main Authors: Purhonen, Susanna, Palm, Jarmo, Rossi, Derrick, Kaskenpää, Nina, Rajantie, Iiro, Ylä-Herttuala, Seppo, Alitalo, Kari, Weissman, Irving L., Salven, Petri
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2365563/
https://ncbi.nlm.nih.gov/pubmed/18443294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0710516105
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