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Are animal models useful for studying human disc disorders/degeneration?

Intervertebral disc (IVD) degeneration is an often investigated pathophysiological condition because of its implication in causing low back pain. As human material for such studies is difficult to obtain because of ethical and government regulatory restriction, animal tissue, organs and in vivo mode...

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Main Authors: Alini, Mauro, Eisenstein, Stephen M., Ito, Keita, Little, Christopher, Kettler, A. Annette, Masuda, Koichi, Melrose, James, Ralphs, Jim, Stokes, Ian, Wilke, Hans Joachim
格式: Artigo
語言:Inglês
出版: Springer-Verlag 2007
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2365516/
https://ncbi.nlm.nih.gov/pubmed/17632738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00586-007-0414-y
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