Are animal models useful for studying human disc disorders/degeneration?

Intervertebral disc (IVD) degeneration is an often investigated pathophysiological condition because of its implication in causing low back pain. As human material for such studies is difficult to obtain because of ethical and government regulatory restriction, animal tissue, organs and in vivo mode...

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Hlavní autoři: Alini, Mauro, Eisenstein, Stephen M., Ito, Keita, Little, Christopher, Kettler, A. Annette, Masuda, Koichi, Melrose, James, Ralphs, Jim, Stokes, Ian, Wilke, Hans Joachim
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer-Verlag 2007
Témata:
Review
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2365516/
https://ncbi.nlm.nih.gov/pubmed/17632738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00586-007-0414-y
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