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Human cytomegalovirus DNA replicates after early circularization by concatemer formation, and inversion occurs within the concatemer.

To determine the replicative mechanism for human cytomegalovirus (HCMV) DNA, field inversion gel electrophoresis was used to separate HCMV replicative DNAs during lytic infection. Unit-length circular HCMV genomes lacking terminal restriction fragments were detected starting 4 h after infection even...

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Bibliographic Details
Published in:J Virol
Main Authors: McVoy, M A, Adler, S P
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1994
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236542/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8289333/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.2.1040-1051.1994
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