NPC 15669 blocks neutrophil CD18 increase and lung injury during cardiopulmonary bypass in pigs

During cardiopulmonary bypass (CPB), neutrophils become activated due to contact with extracorporeal surfaces and binding of complement fragments C3a and C5a, leading to extravasation and subsequent tissue damage. In this study, the effects of the leumedin NPC 15669 (N [9H - (2,7 dimethylfluorenyl -...

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Autors principals: Bator, J. M., Gillinov, A. M., Zehr, K. J., Redmond, J. M., Wilson, I. C., Herskowitz, A., Connor, J. R., Burch, R. M., Cameron, D. E.
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 1993
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2365389/
https://ncbi.nlm.nih.gov/pubmed/18475516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/S0962935193000201
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