Negative-strand RNA transcripts are produced in human immunodeficiency virus type 1-infected cells and patients by a novel promoter downregulated by Tat.

Current understanding of human immunodeficiency virus type 1 (HIV-1) transcription is based on unidirectional expression of transcripts with positive-strand polarity from the 5' long terminal repeat. We now report HIV-1 transcripts with negative-strand polarity obtained from acutely and chronic...

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Detalhes bibliográficos
Main Authors: Michael, N L, Vahey, M T, d'Arcy, L, Ehrenberg, P K, Mosca, J D, Rappaport, J, Redfield, R R
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC236536/
https://ncbi.nlm.nih.gov/pubmed/8289399
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