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Tumour necrosis factor (TNF) and interleukin-1 (IL-1) induce muscle proteolysis through different mechanisms

The purpose of this study was to test the hypothesis that muscle proteolysis induced by TNF or IL-1 is mediated by glucocorticoids. Rats were treated with 300 μg kg(−1) of recombinant human preparations of IL-1α (rIL-1α) or TNFα (rTNFα) divided into three equal intraperitoneal doses given over 16 h....

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Main Authors: Zamir, Oded, Hasselgren, Per-Olof, Higashiguchi, Takashi, Frederick, Janice A., Fischer, Josef E.
Formato: Artigo
Idioma:Inglês
Publicado: Hindawi Publishing Corporation 1992
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2365344/
https://ncbi.nlm.nih.gov/pubmed/18475468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/S0962935192000371
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