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Oligonucleotides Modified With Transplatin Derivatives: Fast and Efficient Metalloribozymes
When an oligonucleotide containing a 1,3-(G,G)-transplatin cross-link at a GNG site (N represents a C, T, A or U residue) is paired with its complementary strand, the intrastrand adduct rearranges into an interstrand cross-link, resulting in the covalent attachment of both strands. Here, we have stu...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Hindawi Publishing Corporation
2001
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2365245/ https://ncbi.nlm.nih.gov/pubmed/18475974 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/MBD.2001.39 |
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