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Oligonucleotides Modified With Transplatin Derivatives: Fast and Efficient Metalloribozymes

When an oligonucleotide containing a 1,3-(G,G)-transplatin cross-link at a GNG site (N represents a C, T, A or U residue) is paired with its complementary strand, the intrastrand adduct rearranges into an interstrand cross-link, resulting in the covalent attachment of both strands. Here, we have stu...

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Detalhes bibliográficos
Main Authors: Dalbiès-Tran, Rozenn, Leng, Marc, Boudvillain, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2365245/
https://ncbi.nlm.nih.gov/pubmed/18475974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/MBD.2001.39
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