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A Screening Strategy for Metal Antitumor Agents as Exemplified by Gold(III) Complexes

The use of a screening strategy based on human tumor cell lines, which are also tumorigenic in immune-deprived mice, is described. Activity against the human tumor cells in vitro and in vivo, is complemented with studies on the mechanism of action. This aporoach is demonstrated using 2-[(dimethylami...

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Autor principal: Fricker, Simon P.
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 1999
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2365177/
https://ncbi.nlm.nih.gov/pubmed/18475904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/MBD.1999.291
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