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The genomic instability associated with integrated simian virus 40 DNA is dependent on the origin of replication and early control region.

DNA rearrangements in the form of deletions and duplications are found within and near integrated simian virus 40 (SV40) DNA in nonpermissive cell lines. We have found that rearrangements also occur frequently with integrated pSV2neo plasmid DNA. pSV2neo contains the entire SV40 control region, incl...

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Bibliographic Details
Published in:J Virol
Main Authors: Hunter, D J, Gurney, E G
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1994
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236515/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8289382/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.2.787-796.1994
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