Transepithelial Transport and Metabolism of Boronated Dipeptides Across Caco-2 and HCT-8 Cell Monolayers

Oral delivery of proteins and peptides as therapeutic agents is problematic due to their low bioavailability. This study examined the effect of boronation on the transepithelial transport and metabolism of three glycine-phenylalanine dipeptides in Caco-2 and HCT-8 cell monolayers. The three dipeptid...

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Detalhes bibliográficos
Main Authors: Elkins, Amy L., Eley, John G., Miller III, Merrill C., Hall, Iris H., Sood, Anup, Spielvogel, Bernard
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 1996
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2365028/
https://ncbi.nlm.nih.gov/pubmed/18475758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/MBD.1996.277
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