Extent of the Acidification by N7-Coordinated cis-Diammine-Platinum(II) on the Acidic Sites of Guanine Derivatives

Coordination of two monoprotonated 2'-deoxyguanosine 5'-monophosphate species, H(dGMP)(−), via N7 to cis-(NH(2))(2)Pt(2+) gives the complex cis-(NH(2))(2)Pt(H·dGMP)(2) which is a four-protonic acid. The corresponding acidity constants were measured by potentiometric pH titrations (25℃; I =...

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Hlavní autoři: Song, Bin, Oswald, Gerda, Bastian, Matthias, Sigel, Helmut, Lippert, Bernhard
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 1996
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2365022/
https://ncbi.nlm.nih.gov/pubmed/18472808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/MBD.1996.131
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