A small and efficient dimerization/packaging signal of rat VL30 RNA and its use in murine leukemia virus-VL30-derived vectors for gene transfer.

Retroviral genomes consist of two identical RNA molecules associated at their 5' ends by the dimer linkage structure located in the packaging element (Psi or E) necessary for RNA dimerization in vitro and packaging in vivo. In murine leukemia virus (MLV)-derived vectors designed for gene transf...

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Publicado en:J Virol
Autores principales: Torrent, C, Gabus, C, Darlix, J L
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 1994
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236500/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8289369/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.2.661-667.1994
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