An Investigation of 2′-Deoxyribonucleoside Cyanoboranes in Mice for Therapeutic Safety

A standard acute toxicity study was undertaken to assess 2′-deoxyribonucleoside cyanoboranes for therapeutic safety. 2′-Deoxyribonucleoside cyanoboranes and related derivatives were nontoxic at doses required for anti-neoplastic and hypolipidemic activities. At higher doses (50 and 100 mg/kg/day IP...

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Main Authors: Hall, Iris H., Burnham, Bruce S., Rajendran, K. G., Chang, J.-J., Sood, Anup, Spielvogel, Bernard
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 1994
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2364877/
https://ncbi.nlm.nih.gov/pubmed/18476214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/MBD.1994.19
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