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Oestrogen inhibits resveratrol-induced post-translational modification of p53 and apoptosis in breast cancer cells
Resveratrol, a naturally occurring stilbene, induced apoptosis in human breast cancer MCF-7 cells. The mechanism of this effect was dependent on mitogen-activated protein kinase (MAPK, ERK1/2) activation and was associated with serine phosphorylation and acetylation of p53. Treatment of MCF-7 cells...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2364738/ https://ncbi.nlm.nih.gov/pubmed/15188005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601902 |
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