CENP-E combines a slow, processive motor and a flexible coiled coil to produce an essential motile kinetochore tether

The mitotic kinesin centromere protein E (CENP-E) is an essential kinetochore component that directly contributes to the capture and stabilization of spindle microtubules by kinetochores. Although reduction in CENP-E leads to high rates of whole chromosome missegregation, neither its properties as a...

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Bibliographic Details
Main Authors: Kim, Yumi, Heuser, John E., Waterman, Clare M., Cleveland, Don W.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2008
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2364708/
https://ncbi.nlm.nih.gov/pubmed/18443223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200802189
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