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Genome Sequence of Brucella abortus Vaccine Strain S19 Compared to Virulent Strains Yields Candidate Virulence Genes

The Brucella abortus strain S19, a spontaneously attenuated strain, has been used as a vaccine strain in vaccination of cattle against brucellosis for six decades. Despite many studies, the physiological and molecular mechanisms causing the attenuation are not known. We have applied pyrosequencing t...

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Detalhes bibliográficos
Main Authors: Crasta, Oswald R., Folkerts, Otto, Fei, Zhangjun, Mane, Shrinivasrao P., Evans, Clive, Martino-Catt, Susan, Bricker, Betsy, Yu, GongXin, Du, Lei, Sobral, Bruno W.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2364660/
https://ncbi.nlm.nih.gov/pubmed/18478107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002193
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