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Marked variation in predicted and observed variability of tandem repeat loci across the human genome

BACKGROUND: Tandem repeat (TR) variants in the human genome play key roles in a number of diseases. However, current models predicting variability are based on limited training sets. We conducted a systematic analysis of TRs of unit lengths 2–12 nucleotides in Whole Genome Shotgun (WGS) sequences to...

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Autors principals: O'Dushlaine, Colm T, Shields, Denis C
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2364633/
https://ncbi.nlm.nih.gov/pubmed/18416815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-9-175
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