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Site-directed mutagenesis of a conserved hexapeptide in the paramyxovirus hemagglutinin-neuraminidase glycoprotein: effects on antigenic structure and function.

The sequence NRKSCS constitutes the longest linear stretch in the amino acid sequence of the hemagglutinin-neuraminidase (HN) glycoprotein of the paramyxoviruses that is completely conserved among all viruses in the group. We have used site-directed mutagenesis and expression of the mutated HN prote...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Mirza, A M, Deng, R, Iorio, R M
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1994
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236452/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8035509/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.8.5093-5099.1994
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