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Association of p53 codon 72 polymorphism with advanced lung cancer: the Arg allele is preferentially retained in tumours arising in Arg/Pro germline heterozygotes

The association of p53 codon 72 polymorphism with cancer has been investigated by several scientific groups with controversial results. In the present study, we examined the genotypic frequency of this polymorphism in 54 patients with advanced lung cancer and 99 normal controls from the geographical...

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Main Authors: Papadakis, E D, Soulitzis, N, Spandidos, D A
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2002
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2364333/
https://ncbi.nlm.nih.gov/pubmed/12434294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600595
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