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Anastrozole (‘Arimidex’) blocks oestrogen synthesis both peripherally and within the breast in postmenopausal women with large operable breast cancer

The effect of anastrozole on peripheral and tumour aromatase activity and oestrogen levels in postmenopausal patients with oestrogen receptor-rich breast tumours was investigated. Twenty-six patients were randomly allocated to treatment with anastrozole 1 mg (n=13) or 10 mg (n=13), once daily. Befor...

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Detalles Bibliográficos
Main Authors: Miller, W R, Stuart, M, Sahmoud, T, Dixon, J M
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2002
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2364315/
https://ncbi.nlm.nih.gov/pubmed/12434282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600587
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