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The herpes simplex virus regulatory protein ICP27 contributes to the decrease in cellular mRNA levels during infection.

We have previously shown that the herpes simplex virus immediate-early regulatory protein ICP27 acts posttranscriptionally to affect mRNA processing (R. M. Sandri-Goldin and G. E. Mendoza, Genes Dev. 6:848-863, 1992). Specifically, in the presence of ICP27, spliced target mRNAs were decreased 5- to...

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Autors principals: Hardwicke, M A, Sandri-Goldin, R M
Format: Artigo
Idioma:Inglês
Publicat: 1994
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC236419/
https://ncbi.nlm.nih.gov/pubmed/8035480
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