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Analysis of the cytochrome c-dependent apoptosis apparatus in cells from human pancreatic carcinoma

Defects in the apoptotic system are likely to play a role in tumorigenesis. Pancreatic carcinoma cells are extremely resistant to apoptosis induction by chemotherapy suggesting that the apoptosis machinery is faulty. We investigated the integrity of the cytochrome c-dependent apoptotic apparatus in...

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Detalhes bibliográficos
Main Authors: Gerhard, M C, Schmid, R M, Häcker, G
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2364161/
https://ncbi.nlm.nih.gov/pubmed/11953820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600171
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