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TNF-α is involved in activating DNA fragmentation in skeletal muscle

Intraperitoneal administration of 100 μg kg(−1) (body weight) of tumour necrosis factor-α to rats for 8 consecutive days resulted in a significant decrease in protein content, which was concomitant with a reduction in DNA content. Interestingly, the protein/DNA ratio was unchanged in the skeletal mu...

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Detalhes bibliográficos
Main Authors: Carbó, N, Busquets, S, van Royen, M, Alvarez, B, López-Soriano, F J, Argilés, J M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2364144/
https://ncbi.nlm.nih.gov/pubmed/11953838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600167
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