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Circadian optimisation of irinotecan and oxaliplatin efficacy in mice with Glasgow osteosarcoma
The relevance of circadian rhythms in irinotecan and oxaliplatin tolerability was investigated with regard to antitumour activity. Mice bearing Glasgow osteosarcoma (GOS) received single agent irinotecan (50 or 60 mg kg(−1) per day) or oxaliplatin (4 or 5.25 mg kg(−1) per day) at one of six dosing t...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2002
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2364142/ https://ncbi.nlm.nih.gov/pubmed/11953836 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600168 |
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