Pemetrexed disodium in recurrent locally advanced or metastatic squamous cell carcinoma of the head and neck

This phase II study determined response rate of patients with locally advanced or metastatic head and neck cancer treated with pemetrexed disodium, a new multitargeted antifolate that inhibits thymidylate synthase, dihydrofolate reductase and glycinamide ribonucleotide formyl transferase. 35 patient...

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Autors principals: Pivot, X, Raymond, E, Laguerre, B, Degardin, M, Cals, L, Armand, J P, Lefebvre, J L, Gedouin, D, Ripoche, V, Kayitalire, L, Niyikiza, C, Johnson, R, Latz, J, Schneider, M
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2001
Matèries:
Regular Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2364119/
https://ncbi.nlm.nih.gov/pubmed/11531245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2001.2010
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