Prostate epithelial cell lines form spheroids with evidence of glandular differentiation in three-dimensional Matrigel cultures

Normal (PNT2-C2) and metastatic (PC-3) prostate cell lines were grown in Matrigel to observe the effects on morphology and phenotype in comparison to monolayer culture. In monolayer cultures, PNT2-C2 showed typical round/cuboidal epithelial morphology, with tight cell associations, whereas in Matrig...

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Bibliographic Details
Main Authors: Lang, S H, Sharrard, R M, Stark, M, Villette, J M, Maitland, N J
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2001
Subjects:
Regular Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2364090/
https://ncbi.nlm.nih.gov/pubmed/11506501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2001.1967
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