Metabolism and growth inhibition of four retinoids in head and neck squamous normal and malignant cells

Isotretinoin (13- cis -retinoic acid, 13cRA) has proven to be active in chemoprevention of head and neck squamous cell carcinoma (HNSCC). Moreover, both all-trans-retinoic acid (ATRA) and 13cRA induce objective responses in oral premalignant lesions. After binding of retinoids to retinoic acid recep...

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Detalhes bibliográficos
Main Authors: Klaassen, I, Brakenhoff, R H, Smeets, S J, Snow, G B, Braakhuis, B J M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2001
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2364086/
https://ncbi.nlm.nih.gov/pubmed/11506507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2001.1952
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