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HPV presence precedes abnormal cytology in women developing cervical cancer and signals false negative smears

In a retrospective case–control study, we investigated high-risk HPV DNA presence by general primer GP5+/6+ PCR in the last normal cervical smear in the patient archives (i.e. baseline smear) of 57 women who later developed cervical cancer. Also, normal cervical smears of 114 age-matched control wom...

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Hlavní autoři: Zielinski, G D, Snijders, P J F, Rozendaal, L, Voorhorst, F J, Linden, H C van der, Runsink, A P, Schipper, F A de, Meijer, C J L M
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2001
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2364067/
https://ncbi.nlm.nih.gov/pubmed/11487272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2001.1926
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