Chimaeric Lym-1 monoclonal antibody-mediated cytolysis by neutrophils from G-CSF-treated patients: stimulation by GM-CSF and role of Fcγ-receptors

Chimaeric Lym-1 (chLym-1) is a monoclonal antibody generated by fusing the variable region genes of murine Lym-1 to human γ1 and κ constant regions. Owing to its selectivity and avidity for human malignant B cells, it is an attractive candidate for developing immune-interventions in B-lymphomas. In...

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Bibliografske podrobnosti
Main Authors: Ottonello, L, Epstein, A L, Mancini, M, Tortolina, G, Dapino, P, Dallegri, F
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2001
Teme:
Regular Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2364058/
https://ncbi.nlm.nih.gov/pubmed/11487281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2000.1940
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