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Photosensitization and mechanism of cytotoxicity induced by the use of ALA derivatives in photodynamic therapy

The use of more lipophilic derivatives of 5-aminolevulinic acid (ALA) is expected to have better diffusing properties, and after conversion into the parent ALA, to reach a higher protoporphyrin IX (PPIX) formation rate, thus improving the efficacy of topical photodynamic therapy (PDT). Here we have...

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Bibliographic Details
Main Authors: Casas, A, Fukuda, H, Di Venosa, G, Batlle, A
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2001
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2364046/
https://ncbi.nlm.nih.gov/pubmed/11461090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2001.1875
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