Demonstration of mixed properties of RU486 in progesterone receptor (PR)-transfected MDA-MB-231 cells: a model for studying the functions of progesterone analogues

Progesterone antagonist RU486 (mifepristone) has been implicated for many anti-neoplastic and obstetrical applications. But the compound has demonstrated undesired agonist-like effect depending on cell, tissue and species studied. Using PR-transfected breast cancer cells MDA-MB-231, this report desc...

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Detalhes bibliográficos
Main Authors: Lin, V C-L, Aw, S E, Ng, E H, Ng, E H-L, Tan, M G-K
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2001
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2364017/
https://ncbi.nlm.nih.gov/pubmed/11747343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2001.2167
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