Hypoxia in human soft tissue sarcomas: Adverse impact on survival and no association with p53 mutations

Clinical and experimental studies have suggested that tumour hypoxia is associated with poor treatment outcome and that loss of apoptotic potential may play a role in malignant progression of neoplastic cells. The tumour suppressor gene p53 induces apoptosis under certain conditions and microenviron...

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Main Authors: Nordsmark, M, Alsner, J, Keller, J, Nielsen, O S, Jensen, O M, Horsman, M R, Overgaard, J
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2001
Assuntos:
Regular Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363869/
https://ncbi.nlm.nih.gov/pubmed/11308256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2001.1728
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