5-fluorouracil modulated by leucovorin, methotrexate and mitomycin: highly effective, low-cost chemotherapy for advanced colorectal cancer

We have reported that an alternating regimen of bolus and continuous infusion 5-fluorouracil (FU) was superior to bolus FU in terms of response rate and progression-free survival in advanced colorectal cancer. Biochemical modulation was an essential part of this regimen and it was selective for the...

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Detalhes bibliográficos
Main Authors: Sobrero, A, Guglielmi, A, Cirillo, M, Recaldin, E, Frassineti, G L, Aschele, C, Ravaioli, A, Testore, P, Caroti, C, Gallo, L, Pessi, M A, Cortesi, E, Turci, D, Grossi, F, Labianca, R
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2001
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363863/
https://ncbi.nlm.nih.gov/pubmed/11308248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2001.1732
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