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Variation in the E2-binding domain of HPV 16 is associated with high-grade squamous intraepithelial lesions of the cervix
Human papillomaviruses (HPV) are strongly associated with cervical intraepithelial neoplasia (CIN) and invasive cancer mainly through the action of the E6 and E7 viral proteins, transcription of which is down-regulated by the E2 protein. To test the hypothesis that HPV 16 E2 variation is important i...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2001
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2363853/ https://ncbi.nlm.nih.gov/pubmed/11308254 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2001.1695 |
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