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Dexrazoxane significantly impairs the induction of doxorubicin resistance in the human leukaemia line, K562

Dexrazoxane combined with doxorubicin (+ 5-fluorouracil + cyclophosphamide – the FAC regime) leads to a significant decrease in doxorubicin cardiotoxicity and a significant increase in median survival time for patients with advanced breast cancer responsive to FAC. The reason for this increase in su...

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Autors principals: Sargent, J M, Williamson, C J, Yardley, C, Taylor, C G, Hellmann, K
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363849/
https://ncbi.nlm.nih.gov/pubmed/11286477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2001.1697
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