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Bisphosphonates regulate cell growth and gene expression in the UMR 106-01 clonal rat osteosarcoma cell line

Local growth of osteosarcoma involves destruction of host bone by proteolytic mechanisms and/or host osteoclast activation. Osteoclast formation and activity are regulated by osteoblast-derived factors such as the osteoclast differentiating factor, receptor activator of NF-κB ligand (RANKL) and the...

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Библиографические подробности
Главные авторы: Mackie, P S, Fisher, J L, Zhou, H, Choong, P F M
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2001
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363848/
https://ncbi.nlm.nih.gov/pubmed/11286476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2000.1679
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