Development of pulmonary bronchiolo-alveolar adenocarcinomas in transgenic mice overexpressing murine c- myc and epidermal growth factor in alveolar type II pneumocytes

Transgenic mouse models were established to study tumorigenesis of bronchiolo-alveolar adenocarcinomas derived from alveolar type II pneumocytes (AT-II cells). Transgenic lines expressing the murine oncogene c- myc under the control of the lung-specific surfactant protein C promoter developed multif...

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Main Authors: Ehrhardt, A, Bartels, T, Geick, A, Klocke, R, Paul, D, Halter, R
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2001
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Regular Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363807/
https://ncbi.nlm.nih.gov/pubmed/11259097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2000.1676
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