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Telomerase activation cooperates with inactivation of p16 in early head and neck tumorigenesis
Alteration of the p16/pRb pathway may cooperate with telomerase activation during cellular immortalization and tumour progression. We studied p16 expression status by immunohistochemistry and telomerase activity using the TRAP assay in 21 premalignant lesions of the head and neck epithelium as well...
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| Main Authors: | , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group
2001
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2363771/ https://ncbi.nlm.nih.gov/pubmed/11207046 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2000.1647 |
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