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Absence of rearrangements in the BRCA2 gene in human cancers

Mutations of BRCA2 in sporadic breast and ovarian carcinomas are exceedingly rare. This led to the suggestion that large genomic rearrangements could be involved. We performed Southern blots in genomic DNA from 130 primary breast cancers and 83 cancer cell lines (breast, ovarian, pancreatic and smal...

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Detalhes bibliográficos
Main Authors: Chin, S-F, Wang, Q, Puisieux, A, Caldas, C
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363698/
https://ncbi.nlm.nih.gov/pubmed/11161375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2000.1577
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