MDR1 causes resistance to the antitumour drug miltefosine

Miltefosine (hexadecylphosphocholine) is used for topical treatment of breast cancers. It has been shown previously that a high percentage of breast carcinomas express MDR1 or MRP. We investigated the sensitivity of MDR1 -expressing cells to treatment with miltefosine. We show that cells overexpress...

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Detalhes bibliográficos
Main Authors: Rybczynska, M, Liu, R, Lu, P, Sharom, F J, Steinfels, E, Pietro, A Di, Spitaler, M, Grunicke, H, Hofmann, J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2001
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363649/
https://ncbi.nlm.nih.gov/pubmed/11355955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2001.1776
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