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p53 expression in squamous dysplasia associated with carcinoma of the oesophagus: evidence for field carcinogenesis

Squamous epithelial dysplasia is often observed multifocally in the cancerous oesophagus and is presumably considered to be a pre-cancerous lesion. A mutation of the p53 tumour suppressor gene is commonly identified in oesophageal cancer and dysplasia. p53 mutations can be anticipated immunohistoche...

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Détails bibliographiques
Auteurs principaux: Yasuda, M, Kuwano, H, Watanabe, M, Toh, Y, Ohno, S, Sugimachi, K
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2000
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363556/
https://ncbi.nlm.nih.gov/pubmed/10993651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2000.1443
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