Allelic losses in carcinoma in situ and testicular germ cell tumours of adolescents and adults: evidence suggestive of the linear progression model

Testicular germ cell tumours (TGCTs) may arise through a process of multi-step carcinogenesis, and loss of heterozygosity (LOH) at specific loci is likely to be an important early event, although this has not been studied in detail. In order to explore the pathogenetic relationships among TGCTs, we...

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Detalhes bibliográficos
Main Authors: Faulkner, S W, Leigh, D A, Oosterhuis, J W, Roelofs, H, Looijenga, L H J, Friedlander, M L
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2000
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363524/
https://ncbi.nlm.nih.gov/pubmed/10952776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2000.1334
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