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Limitations of the nested reverse transcriptase polymerase chain reaction on tyrosinase for the detection of malignant melanoma micrometastases in lymph nodes

The specificity and sensitivity of the nested reverse transcriptase polymerase chain reaction (RT-PCR) on tyrosinase was studied, for the detection of micrometastases of malignant melanoma. The specificity was assessed in the blood of six healthy donors, four patients with non-melanoma cancers of wh...

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Detalhes bibliográficos
Main Authors: Calogero, A, Timmer-Bosscha, H, Koops, H Schraffordt, Tiebosch, A T M G, Mulder, N H, Hospers, G A P
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363472/
https://ncbi.nlm.nih.gov/pubmed/10901368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2000.1282
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