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Limitations of the nested reverse transcriptase polymerase chain reaction on tyrosinase for the detection of malignant melanoma micrometastases in lymph nodes

The specificity and sensitivity of the nested reverse transcriptase polymerase chain reaction (RT-PCR) on tyrosinase was studied, for the detection of micrometastases of malignant melanoma. The specificity was assessed in the blood of six healthy donors, four patients with non-melanoma cancers of wh...

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Bibliografiske detaljer
Main Authors: Calogero, A, Timmer-Bosscha, H, Koops, H Schraffordt, Tiebosch, A T M G, Mulder, N H, Hospers, G A P
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2000
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363472/
https://ncbi.nlm.nih.gov/pubmed/10901368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2000.1282
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