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Antitumour activity of novel taxanes that act at the same time as cytotoxic agents and P-glycoprotein inhibitors

Taxanes antitumour agents such as paclitaxel and docetaxel represent a successful family of chemotherapeutic drugs. Unfortunately, acquired and innate resistance represents a clinical problem for these drugs. We investigated, on a panel of 7 human cancer cell lines, the growth inhibition effect of 3...

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Detalhes bibliográficos
Main Authors: Ferlini, C, Distefano, M, Pignatelli, F, Lin, S, Riva, A, Bombardelli, E, Mancuso, S, Ojima, I, Scambia, G
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363450/
https://ncbi.nlm.nih.gov/pubmed/11104578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2000.1500
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