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Search for NTRK1 proto-oncogene rearrangements in human thyroid tumours originated after therapeutic radiation

Rearrangements of NTRK1 proto-oncogene were detected in ‘spontaneous’ papillary thyroid carcinomas with a frequency varying from 5 to 25% in different studies. These rearrangements result in the formation of chimaeric genes composed of the tyrosine kinase domain of NTRK1 fused to 5′ sequences of dif...

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Detalhes bibliográficos
Main Authors: Bounacer, A, Schlumberger, M, Wicker, R, Du-Villard, J A, Caillou, B, Sarasin, A, Suárez, H G
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363282/
https://ncbi.nlm.nih.gov/pubmed/10646882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.1999.0920
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