Deficient activation of CD95 (APO-1/ Fas)-mediated apoptosis: a potential factor of multidrug resistance in human renal cell carcinoma

The pronounced resistance of human renal cell carcinoma (RCC) to anticancer-induced apoptosis has primarily been related to the expression of P-glycoprotein and effective drug detoxification mechanisms. Because the CD95 system has recently been identified as a key mediator of anticancer drug-induced...

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Detalhes bibliográficos
Main Authors: Ramp, U, Dejosez, M, Mahotka, C, Czarnotta, B, Kalinski, T, Wenzel, M, Lorenz, I, Müller, M, Krammer, P, Gabbert, H E, Gerharz, C D
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2000
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363218/
https://ncbi.nlm.nih.gov/pubmed/10839301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2000.1155
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